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Article

Increased bone mass is a part of the generalized lymphoproliferative disorder phenotype in the mouse.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 2003

Katavić Vedran, Lukić Ivan Kresimir, Kovacić Natasa, Grcević Danka, Lorenzo Joseph A, Marusić Ana

Abstract excerpt

We investigated the bone phenotype of mice with generalized lymphoproliferative disorder (gld) due to a defect in the Fas ligand-mediated apoptotic pathway. C57BL/6-gld mice had greater whole body bone mineral density and greater trabecular bone volume than their wild-type controls. gld mice lost 5-fold less trabecular bone and had less osteoclasts on bone surfaces after ovariectomy-induced bone resorption. They...

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Source

Identifiers

PMID: 12538719
DOI: 10.4049/jimmunol.170.3.1540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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