Article
The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development.
Bone - 1 Nov 1995
Popoff S N, Marks S C
Abstract excerpt
Experimental studies of the mammalian osteopetroses, characterized by generalized skeletal sclerosis, have illuminated a variety of mechanisms by which bone resorption can be reduced. We review recent data implicating a diverse group of growth factors, proto-oncogenes, and immune regulators that can influence skeletal development and account for the heterogeneity of the osteopetroses. Furthermore, similar studies...
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