The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development.

doi:10.1016/8756-3282(95)00347-4

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Article

The heterogeneity of the osteopetroses reflects the diversity of cellular influences during skeletal development.

Bone - 1 Nov 1995

Popoff S N, Marks S C

Abstract excerpt

Experimental studies of the mammalian osteopetroses, characterized by generalized skeletal sclerosis, have illuminated a variety of mechanisms by which bone resorption can be reduced. We review recent data implicating a diverse group of growth factors, proto-oncogenes, and immune regulators that...

Topics

Adjuvants, Immunologic
Animals
Bone Development
Bone Resorption
Macrophage Colony-Stimulating Factor
Mutation
Osteopetrosis
Proto-Oncogene Proteins

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