Article
[p16 and cyclinD1 protein expression and p16 gene mutation in primary human hepatocellular carcinoma].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University - 28 Dec 2001
Huang G X, Cheng R X, Feng D Y
Abstract excerpt
OBJECTIVE: To elucidate the relationship between expression of p16 and cyclinD1 proteins and evaluate the role of p16 gene exon 2 mutation in hepatocellular carcinogenesis. METHODS: Streptavidin-peroxidase conjugated method(SP) was used to detect expressions of p16 and cyclinD1 proteins in 44 cases of hepatocellular carcinoma(HCC), and polymerase chain reaction single-strand conformation polymorphism...
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