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Article

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.

Pharmacogenetics - 1 Jun 1992

Butler M A, Lang N P, Young J F, Caporaso N E, Vineis P, Hayes R B, Teitel C H, Massengill J P, Lawsen M F, Kadlubar F F

Abstract excerpt

The wide variations in urinary bladder and colo-rectal cancer incidence in humans have been attributed in part to metabolic factors associated with exposure to carcinogenic aromatic and heterocyclic amines. Cytochrome P-4501A2 (CYP1A2), which catalyses N-oxidation, and acetyltransferase (NAT2) which catalyses N- and O-acetylation, both appear to be polymorphically distributed in human populations; and slow and...

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Source

Identifiers

PMID: 1306111
DOI: 10.1097/00008571-199206000-00003

Genes

NAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.PMID 1306111Read ↗

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