Variants in the IL17 pathway genes are associated with atopic asthma and atopy makers in a South American population

Abstract excerpt

Asthma is a complex disorder with multiple phenotypes which can influence its severity and response to treatment. The T H 17 lymphocytes producing IL-17A and IL17-F cytokines, may have a role on asthma inflammation. The aim of our study was to evaluate the association between genetic variants in IL17 pathway genes with asthma and atopy markers. Genotyping was performed using a commercial panel in 1245...

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