How demography shapes linkage disequilibrium with or without recombination

Abstract excerpt

Linkage Disequilibrium (LD) is a measure of the statistical association, within a population, between alleles present at different loci. Here, we produce detailed characterizations of LD statistics in different demographic scenarios, with simulations and with analytic results, focusing on several widely used measures of LD ( D , | D ′|, and r 2 ), and introducing a fourth class of statistics: 2-site configurati...

Topics

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• Algorithms
• ATP Binding Cassette Transporter, Subfamily B, Member 3
• ATP-Binding Cassette Transporters
• Computer Simulation
• Genetic Heterogeneity
• Linkage Disequilibrium
• Population Density
• Recombination, Genetic

Identifiers and source

Literature Corpus work

d8ed3f3e-6b49-5476-a675-30ca458d4c8c

DOI

10.1101/2023.12.13.571342