Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DmMyD88 controls dorsoventral patterning of the Drosophila embryo.

EMBO reports - 1 Jan 2003

Kambris Zakaria, Bilak Hana, D'Alessandro Rosalba, Belvin Marcia, Imler Jean-Luc, Capovilla Maria

Abstract excerpt

MyD88 is an adapter protein in the signal transduction pathway mediated by interleukin-1 (IL-1) and Toll-like receptors. A Drosophila homologue of MyD88 (DmMyD88) was recently shown to be required for the Toll-mediated immune response. In Drosophila, the Toll pathway was originally characterized for its role in the dorsoventral patterning of the embryo. We found that, like Toll, DmMyD88 messenger RNA is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Differentiation
Share to Egg Proteins
Share to Embryo, Nonmammalian

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Morphogenesis

Share to Myeloid Differentiation Factor 88

Share to Receptors, Immunologic

Share to Toll-Like Receptors

Share to Zygote

Source

Open in PubMed Open full text

Identifiers

PMID: 12524523
DOI: 10.1038/sj.embor.embor714
PMCID: PMC1315814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DmMyD88 controls dorsoventral patterning of the Drosophila embryo.PMID 12524523Read ↗

<i>Drosophila</i> MyD88 is an adapter in the Toll signaling pathwaySemantic proximity Read ↗

Regulated assembly of the Toll signaling complex drives Drosophila dorsoventral patterning.Semantic proximity Read ↗

The Toll pathway is required in the epidermis for muscle development in the Drosophila embryo.Semantic proximity Read ↗

Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system.Semantic proximity Read ↗

Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo.Semantic proximity Read ↗

Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo.Semantic proximity Read ↗

The Drosophila toll gene functions zygotically and is necessary for proper motoneuron and muscle development.Semantic proximity Read ↗

Identification and Analysis of a Gene with Potential to Repress the IMD Pathway in Drosophila melanogaster.Semantic proximity Read ↗

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis.Semantic proximity Read ↗

Functional analysis of Toll-related genes in Drosophila.Semantic proximity Read ↗

The protein kinase Pelle mediates feedback regulation in the Drosophila Toll signaling pathway.Semantic proximity Read ↗

The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.