Article
Functional analysis of Toll-related genes in Drosophila.
Development, growth & differentiation - 1 Dec 2010
Yagi Yoshimasa, Nishida Yasuyoshi, Ip Y Tony
Abstract excerpt
The Drosophila genome encodes a total of nine Toll and related proteins. The immune and developmental functions of Toll and 18Wheeler (18W) have been analyzed extensively, while the in vivo functions of the other Toll-related proteins require further investigation. We performed transgenic experiments and found that overexpression of Toll-related genes caused different extents of lethality and developmental...
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