Article
Subpopulations of human dendritic cells display a distinct phenotype and bind differentially to proteins of the extracellular matrix.
European journal of cell biology - 1 Dec 2007
Kohl Kristine, Schnautz Sylvia, Pesch Monika, Klein Elisabeth, Aumailley Monique, Bieber Thomas, Koch Susanne
Abstract excerpt
CD1a(pos) dendritic cells (DCs) and Langerhans cells (LCs) are highly specialized antigen-presenting cells mainly localized in the skin. Various cells have been identified as precursors of cutaneous DCs, but the definitive precursor subpopulations remain to be defined and characterized in detail. In this study, DCs were generated in vitro from monocytes (monocyte-derived DCs, MoDCs) and from CD34(pos) stem cells...
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