Article
Identification of CCR9- murine plasmacytoid DC precursors with plasticity to differentiate into conventional DCs.
Blood - 16 Jun 2011
Schlitzer Andreas, Loschko Jakob, Mair Katrin, Vogelmann Roger, Henkel Lynette, Einwächter Henrik, Schiemann Matthias, Niess Jan-Hendrik, Reindl Wolfgang, Krug Anne
Abstract excerpt
Whereas the final differentiation of conventional dendritic cells (CDCs) from committed precursors occurs locally in secondary lymphoid or peripheral tissues, plasmacytoid dendritic cells (PDCs) are thought to fully develop in the bone marrow from common DC progenitors before migrating to the periphery. In our study, we define, for the first time, a subpopulation of CCR9(-) major histocompatibility complex class...
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