Article
Detection of differentiation- and activation-linked cell surface antigens on cultured mast cell progenitors.
Allergy - 1 Oct 2005
Schernthaner G-H, Hauswirth A W, Baghestanian M, Agis H, Ghannadan M, Worda C, Krauth M-T, Printz D, Fritsch G, Sperr W R, Valent P
Abstract excerpt
BACKGROUND: Mast cells (MC) are multifunctional effector cells of the immune system. They derive from uncommitted CD34(+) hemopoietic progenitor cells (HPC). Depending on the stage of maturation and the environment, MC variably express differentiation- and activation-linked antigens. Little is known, however, about the regulation of expression of such antigens in immature human MC. METHODS: We analyzed expression...
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