Article
Human embryonic epidermis contains a diverse Langerhans cell precursor pool.
Development (Cambridge, England) - 1 Feb 2014
Schuster Christopher, Mildner Michael, Mairhofer Mario, Bauer Wolfgang, Fiala Christian, Prior Marion, Eppel Wolfgang, Kolbus Andrea, Tschachler Erwin, Stingl Georg, Elbe-Bürger Adelheid
Abstract excerpt
Despite intense efforts, the exact phenotype of the epidermal Langerhans cell (LC) precursors during human ontogeny has not been determined yet. These elusive precursors are believed to migrate into the embryonic skin and to express primitive surface markers, including CD36, but not typical LC markers such as CD1a, CD1c and CD207. The aim of this study was to further characterize the phenotype of LC precursors in...
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