Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of human Th17 cell responses through complement receptor 3 (CD11 b/CD18) ligation on monocyte-derived dendritic cells.

Journal of autoimmunity - 1 Aug 2018

Nowatzky Johannes, Manches Olivier, Khan Shaukat Ali, Godefroy Emmanuelle, Bhardwaj Nina

Abstract excerpt

OBJECTIVE: Apoptotic cell receptors contribute to the induction of tolerance by modulating dendritic cell function following the uptake of apoptotic cells or microparticles. Dendritic cells that have bound or ingested apoptotic cells produce only low amounts of pro-inflammatory cytokines and fail to prime effector T cell responses. Specifically, ligation of the apoptotic cell receptor CR3 (CD11 b/CD18) on human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD18 Antigens
Share to Cell Plasticity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coculture Techniques

Share to Immune Tolerance

Share to Immunologic Memory

Share to Immunotherapy, Adoptive

Share to Macrophage-1 Antigen

Share to Th17 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 29908907
DOI: 10.1016/j.jaut.2018.05.005
PMCID: PMC6498856

Genes

ITGAM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of human Th17 cell responses through complement receptor 3 (CD11 b/CD18) ligation on monocyte-derived dendritic cells.PMID 29908907Read ↗

Direct contact with natural killer cells reprograms monocyte-derived dendritic cells into a tolerogenic phenotype.Semantic proximity Read ↗

Monocyte-derived dendritic cells: targets as potent antigen-presenting cells for the design of vaccines against infectious diseases.Semantic proximity Read ↗

Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors.Semantic proximity Read ↗

The complement receptor 3 (CD11b/CD18) agonist Leukadherin-1 suppresses human innate inflammatory signalling.Semantic proximity Read ↗

Chemoresistance of human monocyte-derived dendritic cells is regulated by IL-17A.Semantic proximity Read ↗

Human CD1c+ dendritic cells secrete high levels of IL-12 and potently prime cytotoxic T-cell responses.Semantic proximity Read ↗

Human XCR1+ dendritic cells derived in vitro from CD34+ progenitors closely resemble blood dendritic cells, including their adjuvant responsiveness, contrary to monocyte-derived dendritic cells.Semantic proximity Read ↗

Myeloid dendritic cells: Development, functions, and role in atherosclerotic inflammation.Semantic proximity Read ↗

CD137L dendritic cells induce potent response against cancer-associated viruses and polarize human CD8+ T cells to Tc1 phenotype.Semantic proximity Read ↗

Dendritic cells mediate the induction of polyfunctional human IL17-producing cells (Th17-1 cells) enriched in the bone marrow of patients with myeloma.Semantic proximity Read ↗

Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype.Semantic proximity Read ↗

Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.