Article
HIV-1 subtype C reverse transcriptase and protease genotypes in Zimbabwean patients failing antiretroviral therapy.
AIDS research and human retroviruses - 10 Dec 2002
Kantor Rami, Zijenah Lynn S, Shafer Robert W, Mutetwa Solomon, Johnston Elizabeth, Lloyd Robert, von Lieven Andrea, Israelski Dennis, Katzenstein David A
Abstract excerpt
HIV-1 drug resistance mutations have been identified and characterized mostly in subtype B HIV-1 infection. The extent to which antiretroviral drugs select for drug resistance mutations in non-subtype B HIV-1 is not known. We obtained HIV-1 reverse transcriptase (RT) and protease sequences from 21 Zimbabwean patients failing antiretroviral drug therapy. We compared these sequences with 56 published RT and...
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