Article
Comparison of drug resistance mutations and their interpretation in patients infected with non-B HIV-1 variants and matched patients infected with HIV-1 subtype B.
Journal of acquired immune deficiency syndromes (1999) - 1 Apr 2004
Montes Brigitte, Vergne Laurence, Peeters Martine, Reynes Jacques, Delaporte Eric, Segondy Michel
Abstract excerpt
OBJECTIVE: To compare the prevalence of mutations associated with resistance to antiretroviral drugs and their interpretation in patients infected with non-B HIV-1 variants versus HIV-1subtype B-infected patients with similar treatment regimens. METHODS: The reverse transcriptase (RT) and protease genes of HIV-1 were sequenced, and subtypes were determined by phylogenetic analysis. Each sequence belonging to a...
Topics
- Adult
- Anti-HIV Agents
- Drug Resistance, Viral
- Female
- Genetic Variation
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
