Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In vitro demonstration of cell-to-cell interaction in growth plate cartilage using chondrocytes established from p53-/- mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2003

Nakamata Takeharu, Aoyama Tomoki, Okamoto Takeshi, Hosaka Taisuke, Nishijo Koichi, Nakayama Tomitaka, Nakamura Takashi, Toguchida Junya

Abstract excerpt

Three clonal cell lines (MMR14, MMR17, and MMR32) were established from the costal cartilage derived from p53-/- mice. Expression profiles of cartilage-related molecules in MMR14 and MMR17 were compatible with those in cells of the hypertrophic zone. Prolonged in vitro culture induced the expression of calcification-related genes in both cell lines, but calcified nodules were observed only in MMR14. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Proteins
Share to Cell Communication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chondrocytes

Share to Decorin

Share to Growth Plate

Share to Parathyroid Hormone-Related Protein

Share to Peptide Hormones

Share to Proteoglycans

Source

Identifiers

PMID: 12510810
DOI: 10.1359/jbmr.2003.18.1.97

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In vitro demonstration of cell-to-cell interaction in growth plate cartilage using chondrocytes established from p53-/- mice.PMID 12510810Read ↗

Culture and phenotyping of chondrocytes in primary culture.Semantic proximity Read ↗

Primary culture and phenotyping of murine chondrocytes.Semantic proximity Read ↗

Establishment and characterization of two clonal cell lines derived from murine mandibular condyles.Semantic proximity Read ↗

Establishment of a novel chondrocyte-like cell line derived from transgenic mice harboring the temperature-sensitive simian virus 40 large T-antigen gene.Semantic proximity Read ↗

Meckel's cartilage chondrocytes in organ culture synthesize bone-type proteins accompanying osteocytic phenotype expression.Semantic proximity Read ↗

Stable subclones of the chondrogenic murine cell line MC615 mimic distinct stages of chondrocyte differentiation.Semantic proximity Read ↗

Induction of p16 at sites of cartilage invasion in the SCID mouse coimplantation model of rheumatoid arthritis.Semantic proximity Read ↗

Deletion of p21 expression accelerates cartilage tissue repair via chondrocyte proliferation.Semantic proximity Read ↗

Temporal activation of β-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated.Semantic proximity Read ↗

Subcloning of three osteoblastic cell lines with distinct differentiation phenotypes from the mouse osteoblastic cell line KS-4.Semantic proximity Read ↗

Excess BMP Signaling in Heterotopic Cartilage Forming in Prg4-null TMJ Discs.Semantic proximity Read ↗

Isolation of a stromal cell line from an early passage of a mouse mammary tumor line: a model for stromal parenchymal interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.