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Article

Establishment of a novel chondrocyte-like cell line derived from transgenic mice harboring the temperature-sensitive simian virus 40 large T-antigen gene.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1996

Mataga N, Tamura M, Yanai N, Shinomura T, Kimata K, Obinata M, Noda M

Abstract excerpt

We established a clonal chondrocyte-like cell line (TC6, TC stands for large T immortalized chondrocyte-like cell line) derived from articular cartilage of transgenic mice harboring a temperature-sensitive simian virus 40 large T-antigen gene. TC6 cells exhibited spindle-like or polygonal morphol...

Topics

Animals
Antigens, Polyomavirus Transforming
Cartilage, Articular
Cell Differentiation
Cell Line
Clone Cells
Extracellular Matrix Proteins
Gene Expression
Genes, Viral
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Phenotype

RNA, Messenger

Temperature

Source

Identifiers

PMID: 8915772
DOI: 10.1002/jbmr.5650111108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8915772-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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