Article
Establishment of a novel chondrocyte-like cell line derived from transgenic mice harboring the temperature-sensitive simian virus 40 large T-antigen gene.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1996
Mataga N, Tamura M, Yanai N, Shinomura T, Kimata K, Obinata M, Noda M
Abstract excerpt
We established a clonal chondrocyte-like cell line (TC6, TC stands for large T immortalized chondrocyte-like cell line) derived from articular cartilage of transgenic mice harboring a temperature-sensitive simian virus 40 large T-antigen gene. TC6 cells exhibited spindle-like or polygonal morphology and grew well at 33 degrees C in alpha-minimal essential medium supplemented with 0.5% fetal bovine serum. After...
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