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Article

Isolation of a stromal cell line from an early passage of a mouse mammary tumor line: a model for stromal parenchymal interactions.

Journal of cellular physiology - 1 Mar 2005

Lamb Caroline A, Fabris Victoria, Gorostiaga María Alicia, Helguero Luisa A, Efeyan Alejo, Bottino María Cecilia, Simian Marina, Soldati Rocío, Sanjuan Norberto, Molinolo Alfredo, Lanari Claudia

Abstract excerpt

We have developed a murine mammary tumor cell line, MC4-L4, and after 15 passages, a spindle-shaped population became evident. The cuboidal cells, MC4-L4E, cloned by limit dilution, proved to be epithelial tumor cells. When inoculated in syngeneic mice, they gave rise to invasive metastatic carcinomas expressing estrogen and progesterone receptors. These tumors regressed after anti-progestin treatment and stopped...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15389583
DOI: 10.1002/jcp.20143

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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