Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary culture and phenotyping of murine chondrocytes.

Nature protocols - 1 Jan 2008

Gosset Marjolaine, Berenbaum Francis, Thirion Sylvie, Jacques Claire

Abstract excerpt

The culture of chondrocytes is one of the most powerful tools for exploring the intracellular and molecular features of chondrocyte differentiation and activation. However, chondrocytes tend to dedifferentiate into fibroblasts when they are subcultured, which is a major problem. This protocol, involving primary cultures to limit dedifferentiation, describes two different methods for culturing chondrocytes of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cartilage
Share to Cell Culture Techniques
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chondrocytes

Share to Culture Media

Share to Phenotype

Source

Identifiers

PMID: 18714293
DOI: 10.1038/nprot.2008.95

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary culture and phenotyping of murine chondrocytes.PMID 18714293Read ↗

Culture and phenotyping of chondrocytes in primary culture.Semantic proximity Read ↗

A protocol for the culture and isolation of murine synovial fibroblastsSemantic proximity Read ↗

Human Fetal and Adult Chondrocytes.Semantic proximity Read ↗

Immortalized cell lines from mouse xiphisternum preserve chondrocyte phenotype.Semantic proximity Read ↗

Optimization of chondrocyte isolation and phenotype characterization for cartilage tissue engineering.Semantic proximity Read ↗

Phenotypic differences in murine chondrocyte cell lines derived from mature articular cartilage.Semantic proximity Read ↗

An investigation of primary human cell sources and clinical scaffolds for articular cartilage repairSemantic proximity Read ↗

Development and characterization of a human articular cartilage-derived chondrocyte cell line that retains chondrocyte phenotype.Semantic proximity Read ↗

Immortalized mouse articular cartilage cell lines retain chondrocyte phenotype and respond to both anabolic factor BMP-2 and pro-inflammatory factor IL-1.Semantic proximity Read ↗

Acquisition, culture, and phenotyping of synovial fibroblasts.Semantic proximity Read ↗

P38 mitogen-activated protein kinase promotes dedifferentiation of primary articular chondrocytes in monolayer culture.Semantic proximity Read ↗

Phenotypic analysis and differentiation of murine mesenchymal stem cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.