Article
Stable subclones of the chondrogenic murine cell line MC615 mimic distinct stages of chondrocyte differentiation.
Journal of cellular biochemistry - 15 Oct 2009
Surmann-Schmitt Cordula, Widmann Nathalie, Mallein-Gerin Frédéric, von der Mark Klaus, Stock Michael
Abstract excerpt
Fourteen stable subclones derived from the murine chondrogenic cell line MC615 were established and characterised regarding their differentiation stages and responsivity to BMP2. Based on their gene expression profiles which revealed remarkable variances in Col2a1 and Col10a1 expression, subclones could be grouped into at least three distinct categories. Three representative subclones (4C3, 4C6 and 4H4) were...
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