Article
Radioresistance in oral squamous cell carcinoma with p53 DNA contact mutation.
American journal of clinical oncology - 1 Oct 2003
Yamazaki Yutaka, Chiba Itsuo, Hirai Atsuko, Notani Ken-ichi, Kashiwazaki Haruhiko, Tei Kanchu, Totsuka Yasunori, Iizuka Tadashi, Kohgo Takao, Fukuda Hiroshi
Abstract excerpt
Reliable variables to predict the radiosensitivity of each tumor have not been identified. Recent studies have demonstrated that specific regions of mutations within the core domain of p53 protein correlate with responses to chemotherapy and radiotherapy in some tumor types. In this study, we evaluated the relationship between specific p53 mutations and radiosensitivity in 49 patients with oral squamous cell...
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