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Examining the potential role of DNA polymerases eta and zeta in triplet repeat instability in yeast.

DNA repair - 4 Sept 2002

Dixon Michael J, Lahue Robert S

Abstract excerpt

Triplet repeats undergo frequent mutations in human families afflicted with certain neurodegenerative diseases and also in model organisms. Although the molecular mechanisms of triplet repeat instability are still being identified, it is likely that aberrant DNA synthesis plays an important role. Many DNA polymerases stall at triplet repeat sequences, probably due to the adoption of unusual DNA secondary...

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PMID: 12509280
DOI: 10.1016/s1568-7864(02)00095-2

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TNR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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