Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trinucleotide repeat DNA structures: dynamic mutations from dynamic DNA.

Current opinion in structural biology - 1 Jun 1998

Pearson C E, Sinden R R

Abstract excerpt

Models for the disease-associated expansion of (CTG)n.(CAG)n, (CGG)n.(CCG)n, and (GAA)n.(TTC)n trinucleotide repeats involve alternative DNA structures formed during DNA replication, repair and recombination. These repeat sequences are inherently flexible and can form a variety of hairpins, intramolecular triplexes, quadruplexes, and slipped-strand structures that may be important intermediates and result in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA
Share to DNA Repair

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Models, Genetic

Share to Models, Molecular

Share to Mutation

Share to Nucleic Acid Conformation

Share to Recombination, Genetic

Source

Identifiers

PMID: 9666328
DOI: 10.1016/s0959-440x(98)80065-1

Genes

GAA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trinucleotide repeat DNA structures: dynamic mutations from dynamic DNA.PMID 9666328Read ↗

Dynamic mutation: possible mechanisms and significance in human disease.Semantic proximity Read ↗

Trinucleotide instability: a repeating theme in human inherited disorders.Semantic proximity Read ↗

The complex pathology of trinucleotide repeats.Semantic proximity Read ↗

Triplet repeat DNA structures and human genetic disease: dynamic mutations from dynamic DNA.Semantic proximity Read ↗

Molecular conformations and dynamics of nucleotide repeats associated with neurodegenerative diseases: double helices and CAG hairpin loopsSemantic proximity Read ↗

Trinucleotide repeats: mechanisms and pathophysiology.Semantic proximity Read ↗

Dynamic mutations: a decade of unstable expanded repeats in human genetic disease.Semantic proximity Read ↗

Fourteen and counting: unraveling trinucleotide repeat diseasesSemantic proximity Read ↗

Trinucleotide expansion in disease: why is there a length threshold?Semantic proximity Read ↗

Structures of trinucleotide repeats in human transcripts and their functional implications.Semantic proximity Read ↗

New pathologic mechanisms in nucleotide repeat expansion disordersSemantic proximity Read ↗

DNA structure, mutations, and human genetic disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.