Article

Targeting G-quadruplex DNA in promoters of cardiac function-related genes

2012-01-01

Abstract excerpt

G-quadruplexes (G4) are four-stranded DNA secondary structures, which are involved in a diverse range of biological processes. Although the anti-cancer potential of G4s in promoters of oncogenes has been thoroughly investigated, the functions of promoter G4s in non-cancer-related genes are not well understood. The aims of this thesis are (i) to investigate the biological importance of promoter G4s in cardiac funct...

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Literature Corpus work: 51a8463f-7e51-564a-bb93-1552b5e6723d
DOI: 10.25560/9695

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