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Article

TGF-beta 1 as a genetic susceptibility locus for advanced diabetic nephropathy in type 1 diabetes mellitus: an investigation of multiple known DNA sequence variants.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jan 2003

Ng Daniel P K, Warram James H, Krolewski Andrzej S

Abstract excerpt

BACKGROUND: Transforming growth factor-beta1 (TGF-beta1) is a profibrotic cytokine suspected to be a crucial factor underlying glomerulosclerosis in advanced diabetic nephropathy. However, its potential role as a susceptibility gene for the development of this microvascular complication is unresolved. METHODS: We examined whether DNA sequence variants in the TGF-beta1 gene are associated with advanced diabetic...

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Identifiers

PMID: 12500218
DOI: 10.1053/ajkd.2003.50011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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