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Suggestive Contribution of Sequence Signal Gene Variants of TGF-β1 in Development of Type 1 Diabetes, Diabetic Neuropathy, and Modulation of Lipid Profile.

Biochemical genetics - 1 Jun 2026

Mihoubi Esma, Bouldjennet Faiza, Amroun Habiba, Azzouz Malha, Touil-Boukoffa Chafia, Raache Rachida

Abstract excerpt

Type 1 diabetes mellitus (T1DM) and its associated complications result from the interplay between genetic and environmental factors, with inflammation playing a central role in their pathogenesis. This study aimed to assess the association between TGF-β1 gene variants and T1DM, as well as its neuropathy, in the Algerian population. A case-control study was conducted, analyzing 344 blood samples. The TGF-β1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40879861
DOI: 10.1007/s10528-025-11240-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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