Article
Association of TGF-beta1 polymorphisms with chronic renal disease.
Journal of nephrology - 1 Jan 2000
Coll Elisabeth, Cormand Bru, Campos Begoña, González-Núñez Daniel, Iñigo Pablo, Botey Albert, Poch Esteban
Abstract excerpt
BACKGROUND: Transforming growth factor beta1 (TGF-beta1) plays an important role in tissue fibrosis and has been found to participate in cardiovascular disease (CVD). This study aimed to evaluate the association of TGF-beta1 polymorphisms with chronic renal disease (CRD), and its progression to dialysis in a retrospective longitudinal study of an end-stage renal disease (ESRD) cohort. METHODS: The Arg/Pro (codon...
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