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Significant Association of Candidate Genes (AGTR1 and TGF-Β1) Polymorphism with Diabetic Nephropathy in Diabetes Mellitus Type 2 Patients.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 6 May 2024

Ihsan Madeeha, Khan Najeeb Ullah, Asim Noreen, Ismail Muhammad, Almutairi Mikhlid H, Ali Ijaz, Adams Brian D

Abstract excerpt

BACKGROUND/AIMS: Diabetic nephropathy (DN) is one of the complications of diabetes mellitus (DM). This study aimed to investigate the association between genetic polymorphisms, specifically AGTR1 (rs5186) and TGF-β1 (rs1800470), and the risk of developing Diabetic nephropathy (DN) in type 2 diabetes mellitus patients, compared to those without DN and healthy controls. METHODS: A case-control study was conducted...

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PMID: 38852191
DOI: 10.33594/000000702

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