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Article

7-OH-DPAT and PD 128907 selectively activate the D3 dopamine receptor in a novel environment.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2003

Pritchard Laurel M, Logue Aaron D, Hayes Scott, Welge Jeffrey A, Xu Ming, Zhang Jianhua, Berger S Paul, Richtand Neil M

Abstract excerpt

The D3 dopamine receptor is expressed primarily in limbic brain areas, and appears to play an inhibitory role in rodent locomotor behavior. Evidence suggests a potential role for the D3 receptor in the pathology of neuropsychiatric disease. Progress in elucidating D3 receptor function has been hampered, however, by a lack of well-characterized, selective ligands and by conflicting information regarding the...

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PMID: 12496945
DOI: 10.1038/sj.npp.1300018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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