Article
The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder.
Molecular psychiatry - 1 Jul 2004
Avale M E, Falzone T L, Gelman D M, Low M J, Grandy D K, Rubinstein M
Abstract excerpt
The dopamine D4 receptor (D4R) is a candidate gene for attention deficit/hyperactivity disorder (ADHD) based on genetic studies reporting that particular polymorphisms are present at a higher frequency in affected children. However, the direct participation of the D4R in the onset or progression...
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