Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activity, non-selective attention and emotionality in dopamine D2/D3 receptor knock-out mice.

Behavioural brain research - 10 Mar 2002

Vallone D, Pignatelli M, Grammatikopoulos G, Ruocco L, Bozzi Y, Westphal H, Borrelli E, Sadile A G

Abstract excerpt

In order to assess the role of dopamine (DA) D2 and D3 receptors in the modulation of behaviour, we analysed exploration in a spatial novelty in mouse model systems. Genetically engineered mice mutants have been used that carry normal, partial or no expression of D2R, D3R, or both D2R/D3R (double mutants) DA receptor subtypes. Adult male mice were exposed for 30 min to a Làte-maze. The behaviour was analysed for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Attention
Share to Emotions
Share to Environment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exploratory Behavior

Share to Mice, Knockout

Share to Motor Activity

Share to Receptors, Dopamine D2

Share to Receptors, Dopamine D3

Source

Identifiers

PMID: 11864730
DOI: 10.1016/s0166-4328(01)00428-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activity, non-selective attention and emotionality in dopamine D2/D3 receptor knock-out mice.PMID 11864730Read ↗

Modification of dopamine D(1) receptor knockout phenotype in mice lacking both dopamine D(1) and D(3) receptors.Semantic proximity Read ↗

Behavioural assessment of mice lacking D1A dopamine receptors.Semantic proximity Read ↗

Spatial learning deficit in dopamine D(1) receptor knockout mice.Semantic proximity Read ↗

Essential conservation of D1 mutant phenotype at the level of individual topographies of behaviour in mice lacking both D1 and D3 dopamine receptors.Semantic proximity Read ↗

Phenotypic, ethologically based resolution of spontaneous and D(2)-like vs D(1)-like agonist-induced behavioural topography in mice with congenic D(3) dopamine receptor "knockout".Semantic proximity Read ↗

The contribution of comparative studies in inbred strains of mice to the understanding of the hyperactive phenotype.Semantic proximity Read ↗

Topographical evaluation of behavioural phenotype in a line of mice with targeted gene deletion of the D2 dopamine receptor.Semantic proximity Read ↗

Topographical evaluation of the phenotype of spontaneous behaviour in mice with targeted gene deletion of the D1A dopamine receptor: paradoxical elevation of grooming syntax.Semantic proximity Read ↗

Reduced attention and increased impulsivity in mice lacking NPY Y2 receptors: relation to anxiolytic-like phenotype.Semantic proximity Read ↗

7-OH-DPAT and PD 128907 selectively activate the D3 dopamine receptor in a novel environment.Semantic proximity Read ↗

Comparative, topographically-based evaluation of behavioural phenotype and specification of D(1)-like:D(2) interactions in a line of incipient congenic mice with D(2) dopamine receptor 'knockout'.Semantic proximity Read ↗

Dopamine D1 and D3 Receptors Modulate Heroin-Induced Cognitive Impairment through Opponent Actions in Mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.