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Article

Primary malignant lymphoma of the brain: mutation pattern of rearranged immunoglobulin heavy chain gene.

Japanese journal of cancer research : Gann - 1 Dec 2002

Endo Sumio, Zhang Shu-Jing, Saito Takafumi, Kouno Mitsuo, Kuroiwa Toshihiko, Washiyama Kazuo, Kumanishi Toshiro

Abstract excerpt

Using reverse transcription-polymerase chain reaction (RT-PCR), six primary brain lymphomas, pathologically diagnosed as diffuse large B-cell lymphoma, were examined for rearranged VH-D-JH sequences of the immunoglobulin heavy chain gene, focusing on somatic mutations and intraclonal heterogeneity. The reliability of the isolated PCR clones was confirmed by in situ hybridization (ISH) with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12495470
DOI: 10.1111/j.1349-7006.2002.tb01239.x
PMCID: PMC5926927

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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