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Article

Primary central nervous system lymphoma: tumor-related clones exist in the blood and bone marrow with evidence for separate development.

Blood - 7 May 2009

McCann Katy J, Ashton-Key Margaret, Smith Kellyann, Stevenson Freda K, Ottensmeier Christian H

Abstract excerpt

Primary central nervous system (CNS) lymphoma is an aggressive B-cell tumor that is defined clinically by the absence of systemic disease. We have used immunoglobulin variable (V)-gene analysis to identify tumor cells at the CNS site in 12 cases and to probe the involvement of peripheral tissues in 3 patients. Clonal tracking revealed tumor cells in the bone marrow and/or blood for 3 of 3 cases, with evidence for...

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Source

Identifiers

PMID: 19096008
DOI: 10.1182/blood-2008-09-179366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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