Article
Comparative studies of somatic and ongoing mutations in immunoglobulin heavy-chain variable region genes in diffuse large B-cell lymphomas of the stomach and the small intestine.
Archives of pathology & laboratory medicine - 1 Nov 2003
Go Jai Hyang, Kim Dae Shick, Kim Tae Jin, Ko Young H, Ra Hyun Ki, Rhee Jong Chul, Kim Seon Woo, Ree Howe J
Abstract excerpt
CONTEXT: Many diffuse large B-cell lymphomas (DLBCLs) of the stomach are believed to represent high-grade transformation of low-grade marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type, which is of memory B-cell origin, displaying evidence for positive antigen selection and a low level of ongoing somatic mutation of the rearranged immunoglobulin heavy-chain variable region (V(H)) genes. The...
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