Article
Targeted deletion of genes encoding extracellular enzymes in Bacillus licheniformis and the impact on the secretion capability.
Journal of biotechnology - 15 Jun 2007
Waldeck Jens, Meyer-Rammes Heike, Wieland Susanne, Feesche Jörg, Maurer Karl-Heinz, Meinhardt Friedhelm
Abstract excerpt
The general secretory pathway is routinely concerned with a multitude of extracellular enzymes. By eliminating obstructive competitors the export machinery may transport larger quantities of remaining proteins under circumstances in which the secretion machinery is fully loaded. Hence, in this study, genes encoding efficiently expressed but dispensable exoenzymes were knocked out in Bacillus licheniformis MD1....
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