Article
Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering.
Applied and environmental microbiology - 1 Sept 2014
Liu Zihe, Liu Lifang, Österlund Tobias, Hou Jin, Huang Mingtao, Fagerberg Linn, Petranovic Dina, Uhlén Mathias, Nielsen Jens
Abstract excerpt
The increasing demand for industrial enzymes and biopharmaceutical proteins relies on robust production hosts with high protein yield and productivity. Being one of the best-studied model organisms and capable of performing posttranslational modifications, the yeast Saccharomyces cerevisiae is widely used as a cell factory for recombinant protein production. However, many recombinant proteins are produced at only...
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