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Article

Stereospecific analysis of omeprazole in human plasma as a probe for CYP2C19 phenotype.

Journal of pharmaceutical and biomedical analysis - 15 Jan 2003

Kanazawa Hideko, Okada Akiko, Higaki Megumu, Yokota Hiromitsu, Mashige Fumiko, Nakahara Kazuhiko

Abstract excerpt

Omeprazole is a class referred to as proton pump inhibitor; it acts to regulate acid production in the stomach and is used to treat various acid-related gastrointestinal disorders. In the liver, it is metabolized to varying degrees by several cytochrome P-450 (CYP) isoenzymes which are further categorized into subfamilies of related polymorphic gene products. The metabolism of omeprazole is to a large extent...

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Identifiers

PMID: 12485723
DOI: 10.1016/s0731-7085(02)00524-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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