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Article

Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor.

The Journal of biological chemistry - 14 Feb 2003

Schmidt Ulrike, Wochnik Gabriela M, Rosenhagen Marcus C, Young Jason C, Hartl F Ulrich, Holsboer Florian, Rein Theo

Abstract excerpt

The co-chaperone BAG-1 is involved in the regulation of steroid hormone receptors, including the glucocorticoid receptor (GR). More recently, BAG-1 was found in the nucleus where it decreases GR transactivation. Moreover, nonspecific DNA binding of BAG-1 has been reported. We discovered that of t...

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Source

Identifiers

PMID: 12482863
DOI: 10.1074/jbc.M212000200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12482863-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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