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Article

RREB-1 Is a Transcriptional Repressor of HLA-G

4 Nov 2009

Abstract excerpt

The nonclassical HLA-G is a molecule specifically involved in immune tolerance with highly restricted tissue distribution in healthy conditions. Yet it is overexpressed in numerous tumors and in allografts with better acceptance. Major mechanisms involved in regulation of HLA-G transcription are still poorly described. Thus, to characterize these mechanisms we have developed a specific proteomic approach to...

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Identifiers

PMID: 19890057
DOI: 10.4049/jimmunol.0902053

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