Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of E2A activities by histone acetyltransferases in B lymphocyte development.

The Journal of biological chemistry - 24 Jan 2003

Bradney Curtis, Hjelmeland Mark, Komatsu Yasuhiko, Yoshida Minoru, Yao Tso-Pang, Zhuang Yuan

Abstract excerpt

Genetic studies have demonstrated that the basic helix-loop-helix protein E2A is an essential transcription factor in B lymphocyte lineage commitment and differentiation. However, the mechanism underlying E2A-mediated transcription regulation is not fully understood. Here, we investigated the physical and genetic interactions between E2A and co-activators histone acetyltransferases (HATs) in B cells. Gel...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acetyltransferases
Share to Basic Helix-Loop-Helix Transcription Factors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Separation

Share to Chromatography, Gel

Share to E1A-Associated p300 Protein

Share to Histone Acetyltransferases

Share to Luciferases

Share to Precipitin Tests

Source

Identifiers

PMID: 12435739
DOI: 10.1074/jbc.M211464200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of E2A activities by histone acetyltransferases in B lymphocyte development.PMID 12435739Read ↗

Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoter.Semantic proximity Read ↗

Direct Interaction between Nucleosome Assembly Protein 1 and the Papillomavirus E2 Proteins Involved in Activation of TranscriptionSemantic proximity Read ↗

Changes in C-terminal binding protein 2 (CtBP2) corepressor complex induced by E1A and modulation of E1A transcriptional activity by CtBP2.Semantic proximity Read ↗

Structural insights into TAZ2 domain-mediated CBP/p300 recruitment by transactivation domain 1 of the lymphopoietic transcription factor E2A.Semantic proximity Read ↗

differential roles for the E2A activation domains in B lymphocytes and macrophages.Semantic proximity Read ↗

Trans-regulation of histone deacetylase activities through acetylation.Semantic proximity Read ↗

Coordinated but physically separable interaction with H3K27-demethylase and H3K4-methyltransferase activities are required for T-box protein-mediated activation of developmental gene expression.Semantic proximity Read ↗

Functional regulation of GATA-2 by acetylation.Semantic proximity Read ↗

p300 is involved in formation of the TBP-TFIIA-containing basal transcription complex, TAC.Semantic proximity Read ↗

Interactions between p300 and multiple NF-Y trimers govern cyclin B2 promoter function.Semantic proximity Read ↗

E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1.Semantic proximity Read ↗

Functional analysis of AEBP2, a PRC2 Polycomb protein, reveals a Trithorax phenotype in embryonic development and in ESCs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.