A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.

doi:10.1242/dev.065029

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Article

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.

Development (Cambridge, England) - 1 Aug 2011

Sinsimer Kristina S, Jain Roshan A, Chatterjee Seema, Gavis Elizabeth R

Abstract excerpt

Asymmetric mRNA localization is an effective mechanism for establishing cellular and developmental polarity. Posterior localization of oskar in the Drosophila oocyte targets the synthesis of Oskar to the posterior, where Oskar initiates the assembly of the germ plasm. In addition to harboring germline determinants, the germ plasm is required for localization and translation of the abdominal determinant nanos....

Topics

Alleles
Animals
Carrier Proteins
Cytoplasm
Drosophila Proteins
Drosophila melanogaster
Embryo, Nonmammalian
Female
Heterogeneous-Nuclear Ribonucleoproteins
Mutation
Oocytes
Oogenesis
Protein Binding
RNA, Messenger

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Identifiers

PMID: 21752933
DOI: 10.1242/dev.065029
PMCID: PMC3143563

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