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Article

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.

Development (Cambridge, England) - 1 Mar 2008

Tanaka Tsubasa, Nakamura Akira

Abstract excerpt

Cell fate is often determined by the intracellular localization of RNAs and proteins. In Drosophila oocytes, oskar (osk) RNA localization and the subsequent Osk synthesis at the posterior pole direct the assembly of the pole plasm, where factors for the germline and abdomen formation accumulate. osk RNA produces two isoforms, long and short Osk, which have distinct functions in pole plasm assembly. Short Osk...

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PMID: 18272590
DOI: 10.1242/dev.017293

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly.PMID 18272590Read ↗

A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin.Semantic proximity Read ↗

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.Semantic proximity Read ↗

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oskar mRNA is localized to the posterior pole of the Drosophila oocyte.Semantic proximity Read ↗

The origin of asymmetry: early polarisation of the Drosophila germline cyst and oocyte.Semantic proximity Read ↗

Targeting and anchoring Tudor in the pole plasm of the Drosophila oocyte.Semantic proximity Read ↗

Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole.Semantic proximity Read ↗

The actin-binding protein Lasp promotes Oskar accumulation at the posterior pole of the Drosophila embryo.Semantic proximity Read ↗

PIP5K-dependent production of PIP2 sustains microtubule organization to establish polarized transport in the Drosophila oocyte.Semantic proximity Read ↗

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