Article
Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.
Cell - 12 Jul 1991
Ephrussi A, Dickinson L K, Lehmann R
Abstract excerpt
Oskar is one of seven Drosophila maternal-effect genes that are necessary for germline and abdomen formation. We have cloned oskar and show that oskar RNA is localized to the posterior pole of the oocyte when germ plasm forms. This polar distribution of oskar RNA is established during oogenesis in three phases: accumulation in the oocyte, transport toward the posterior, and finally maintenance at the posterior...
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