Article
Serum stimulation, cell-cell interactions, and extracellular matrix independently influence smooth muscle cell phenotype in vitro.
The American journal of pathology - 1 Aug 1996
Kato S, Shanley J R, Fox J C
Abstract excerpt
Vascular injury profoundly alters the vessel wall microenvironment, and smooth muscle cells respond with cell cycle re-entry, loss of contractile elements, extracellular matrix remodeling, and altered signaling by endogenous growth factors and their receptors. Environmental cues include stimulati...
Topics
- Actins
- Animals
- Aorta
- Blood Physiological Phenomena
- Blotting, Western
- Cell Communication
- Cell Cycle
- Cells, Cultured
- Collagen
- Extracellular Matrix
- Fibroblast Growth Factor 2
- Fibronectins
- Muscle, Smooth, Vascular
- Myosin Heavy Chains
- Phenotype
- Rats
- Rats, Sprague-Dawley
- Receptors, Fibroblast Growth Factor