Transcriptional Profile of Mechanically Induced Genes in Human Vascular Smooth Muscle Cells

Abstract excerpt

Vascular smooth muscle cells must monitor and respond to their mechanical environment; however, the molecular response of these cells to mechanical stimuli remains incompletely defined. By applying a highly uniform biaxial cyclic strain to cultured cells, we used DNA microarray technology to describe the transcriptional profile of mechanically induced genes in human aortic smooth muscle cells. We first identified...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Adhesion Molecules Research
• Share to Galectins and Cancer Biology
• Share to Protease and Inhibitor Mechanisms