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Article

Contribution of the helix-loop-helix factor Id2 to regulation of vascular smooth muscle cell proliferation.

The Journal of biological chemistry - 1 Mar 2002

Matsumura Martin E, Lobe David R, McNamara Coleen A

Abstract excerpt

Smooth muscle cell (SMC) proliferation plays a key role in vascular proliferative disorders. The molecular mechanisms that control cell cycle entry of SMCs in response to vascular injury are not well understood. Id2 (inhibitor of DNA binding) is a member of the helix-loop-helix (HLH) family of transcription regulators that are known to promote cell cycle progression. Thus, we investigated the role of Id2 in SMC...

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Identifiers

PMID: 11706002
DOI: 10.1074/jbc.M108986200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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