Article
Brca1 and differentiation.
Mutation research - 1 Dec 2002
Kubista Marion, Rosner Margit, Miloloza Angelina, Hofer Katja, Prusa Andrea-Romana, Kroiss Regina, Marton Erika, Hengstschläger Markus
Abstract excerpt
Breast cancer is one of the most frequent malignancies affecting women. The human breast cancer gene 1 (BRCA1) gene is mutated in a distinct proportion of hereditary breast and ovarian cancers. Tumourigenesis in individuals with germline BRCA1 mutations requires somatic inactivation of the remain...
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