Article
Molecular epidemiology in environmental health: the potential of tumor suppressor gene p53 as a biomarker.
Environmental health perspectives - 1 Feb 1997
Semenza J C, Weasel L H
Abstract excerpt
One of the challenges in environmental health is to attribute a certain health effect to a specific environmental exposure and to establish a cause-effect relationship. Molecular epidemiology offers a new approach to addressing these challenges. Mutations in the tumor suppressor gene p53 can shed light on past environmental exposure, and carcinogenic agents and doses can be distinguished on the basis of...
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