p53 and lung cancer.

Article

p53 and lung cancer.

Pathologie-biologie - 1 Dec 1997

Brambilla E, Brambilla C

Abstract excerpt

The malignant transformation of pulmonary epithelial cells is the result of multistep accumulation of genetic and molecular alterations highly related to tobacco carcinogens, involving key mechanisms of proliferation and apoptosis. Clonal expansion is the net result of acceleration of cell divisi...

Topics

Antigens, Neoplasm
Biomarkers, Tumor
Genes, p53
Humans
Lung Diseases
Lung Neoplasms
Mutation
Neuroendocrine Tumors
Prognosis

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