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Article

Opposite effects of background genotype on muscle and liver insulin sensitivity of lipoatrophic mice. Role of triglyceride clearance.

The Journal of biological chemistry - 7 Feb 2003

Colombo Carlo, Haluzik Martin, Cutson Jaime J, Dietz Kelly R, Marcus-Samuels Bernice, Vinson Charles, Gavrilova Oksana, Reitman Marc L

Abstract excerpt

The metabolic phenotype of the A-ZIP/F-1 (AZIP) lipoatrophic mouse is different depending on its genetic background. On both the FVB/N (FVB) and C57BL/6J (B6) backgrounds, AZIP mice have a similarly severe lack of white adipose tissue and comparably increased insulin levels and triglyceride secretion rates. However, on the B6 background, the AZIP mice have less hyperglycemia, lower circulating triglyceride and...

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Identifiers

PMID: 12456680
DOI: 10.1074/jbc.M207665200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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